Praxair China, a subsidiary of Praxair Inc, has signed a contract to supply liquid nitrogen and a state-of-the-art nitrogen cooling system (NCOOL) to the Jiangsu Defeng Pharmaceutical & Chemical Co. Ltd. (Defeng).

Defeng produces active pharmaceutical ingredients and is set to introduce a new product which requires rapid cooling to below –30°C in a large volume reactor. Following a thorough market survey, Defeng selected Praxair China as its product and technology supplier, based on the quality of liquid nitrogen, reliability and the new technology offered by Praxair.

The NCOOL indirect cooling system features the highly efficient Praxair cryogenic heat exchanger, using the heat exchange from nitrogen rather than mechanical refrigeration with minimal moving parts and without having to rely on halogenated coolants such as CFC's or other ozone-depleting substances.

“This new application of the NCOOL technology opens up another segment of the fast growing cryogenic refrigeration market in the pharmaceutical industry,” said David Chow, President of Praxair China.

The NCOOL heat exchanger is used for precision cooling of production freeze-dryers and chemical reactors.